• Increasing age: The risk goes up with advanced age.
  • Hardening and narrowing of arteries:The accumulation of fats and cholesterol in the lining of arteries can hinder blood from getting to the brain, which can lead to stroke or another brain injury.
  • People with diabetes appear to have a higher risk for dementia, as it is a well-proven risk factor for stroke and cardiovascular disease-related events, which in turn increase the risk for vascular dementia.
  • Down syndrome.Many people with Down syndrome develop early- onset AD, with signs of dementia by the time they reach middle age.
  • Genetics:When more than one family member has the disorder, risk increases. Further, a mutation of the gene TREM2 has been found to be common among people with a form of very early onset frontotemporal dementia.
  • High blood pressure has been linked to cognitive decline, stroke, and types of dementia that affect the white matter regions of the brain.
  • Mental illness.Depression has been associated with mild mental impairment and cognitive function decline.
  • Smokers are prone to diseases that slow or stop blood from getting to the brain.
  • Alcohol use:Excessive consumption of alcohol increases risk